CIREEHwiki | Main / Mathematical Modeling

We are currently examining biologically-based models of chemical interactions using kinetic models of receptor-ligand systems. More to come!
Pharmacokinetic modeling, especially of persistent organic pollutants such as PBDEs.
Exposure modeling, e.g., of PBDEs.
I have been interested in cellular automata for a very long time, although I'm not doing much in that field these days except in my teaching.
I teach a course on Mathematical Modeling for Public Health and Medicine (EH820)

Selected Publications:

Howard GJ, Schlezinger JJ, Hahn ME, Webster TF. Generalized Concentration Addition Predicts Joint Effects of Aryl Hydrocarbon Receptor Agonists with Partial Agonists and Competitive Antagonists.Environ Health Perspect. 2010; 118(5):666-672 [Online 22 December 2009]. The full text is freely available doi:10.1289/ehp.0901312.
Howard GJ, Webster TF. Generalized concentration addition: A method for examining mixtures containing partial agonists. Journal of Theoretical Biology 2009; 259:469–477. [Online 5 April 2009]. Abstract: doi:10.1016/j.jtbi.2009.03.030.
Webster TF. Pharmacokinetics of POPs: Simple models with different implications for halflives and steady state levels. Organohalogen Compounds 2006; 68. The full text is freely available here.
Webster T, Vieira V, Schecter A. Estimating Exposure to PBDE-47 via Air, Food and Dust Using Monte Carlo Methods. Organohalogen Compounds 2005; 67: 505-8. The full text is freely available here,
Ozonoff D, Webster T (1997). The lattice diagram and 2 x 2 tables. Toxicology & Industrial Health 1997; 13(2-3): 339-355.
Connett P, Webster T. An estimation of the relative human exposure to 2,3,7,8-TCDD emissions via inhalation and ingestion of cow's milk. Chemosphere 1987; 16:2079-2084 (1987).abstract
My first: a description of some of my work on 3-4 Life, a type of cellular automata, in Robert Wainwright's LIFELINE.

Links:

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