CIREEHwiki | Main / Disease Mapping using Generalized Additive Models

We ran a pre-conference workshop at ISES/ISEE 2010 in Seoul, South Korea.

Downloading R

The workshop used the statistical programming language R. Please download it, along with a few additional libraries, onto your laptop. Directions for Windows and Mac users are here: How to Install R (1.4 MB)

Workshop Data and Code

We applied generalized additive models to synthetic data using R code developed for this workshop. Please download the Zip File and save it onto your laptop so you can use it at the workshop: Data and Code v2 (1.2 MB)

Workshop Slides

The slides from the workshop are now available. Due to the size, they have been separated into two parts. Part 1 describes the methods and part 2 shows examples: Workshop Slides 1 (1.1 MB) Workshop Slides 2 (1.8 MB)

References
References: Basics

Webster T, Vieira V; Weinberg J; Aschengrau A. Method for mapping population-based case-control studies using Generalized Additive Models. International Journal of Health Geographics 2006, 5:26. The full text is freely available here.

References: Statistical Power & Comparisons with Other Methods

Young RL, Weinberg J, Vieira V, Ozonoff A, Webster TF. A power comparison of generalized additive models and the spatial scan statistic in a case-control setting. International Journal of Health Geographics 2010, 9:37. The full text is freely available doi:10.1186/1476-072X-9-37
Young RL, Weinberg J, Ozonoff A, Vieira V, Webster TF. Generalized Additive Models and Inflated Type I Error Rates of Smoother Significance Tests. Computational Statistics & Data Analysis. In press. doi:10.1016/j.csda.2010.05.004.
Ozonoff A, Webster T, Vieira V, Weinberg J, Ozonoff D, Aschengrau A. Cluster detection methods applied to the Upper Cape Cod cancer data. Environmental Health: A Global Access Science Source 2005, 4:19. The full text is freely available here

References: Applications

Vieira VM, Hart JE, Webster TF, Weinberg J, Puett R, Laden F, Costenbader KH, Karlson EW. Association between Residences in U.S. Northern Latitudes and Rheumatoid Arthritis: A Spatial Analysis of the Nurses’ Health Study. Environ Health Perspect. 2010; 957–961. The full text is freely available doi:10.1289/ehp.0901861.
Hoffman K, Webster TF, Weinberg JM, Aschengrau A, Janulewicz PA, White RF, Vieira VM. Spatial analysis of learning and developmental disorders in upper Cape Cod, Massachusetts using generalized additive models. International Journal of Health Geographics 2010, 9:7. The full text is freely available doi:10.1186/1476-072X-9-7.
Vieira VM, Webster TF, Weinberg J, Aschengrau A. Spatial analysis of bladder, kidney, and pancreatic cancer on upper Cape Cod: An application of generalized additive models to case-control data. Environmental Health; 2009, 8:3. The full text is freely available doi: 10.1186/1476-069X-8-3
Vieira V, Webster T, Weinberg J, Aschengrau A, Ozonoff D. Spatial analysis of lung, colorectal, and breast cancer on Cape Cod: An application of generalized additive models to case-control data. Environmental Health: A Global Access Science Source 2005, 4:11. The full text is freely available here.

References: Time-Space Applications

Vieira VM, Webster TF, Weinberg JM, Aschengrau A. Spatial-temporal analysis of breast cancer on Upper Cape Cod, Massachusetts. International Journal of Health Geographics 2008, 7:46. The full text is freely available here.

For more information:
email: Dr. Veronica Vieira, Dept. Environmental Health, Boston University School of Public Health
email: Dr. Tom Webster, Dept. Environmental Health, Boston University School of Public Health